Cones

BigY2: 501829
MDKA Birth: India

Tree Position

R-P312/S116 > Z40481 > ZZ11 > U152/S28 > Z56 > BY3548 > Z43/S366 > Z144 > BY28794 > PF6582 > PF6577 > BY3953

Unique Mutations

The mutations unique to this man are summarized in the table below. Those with a '+' or '*' confidence level are considered by FamilyTreeDNA or FullGenomesCorp to be high quality SNPs/INDELs. For completeness, all other mutations of lesser confidence are included as well. These additional mutations may be useful for distinguishing between very closely related men.

Occasionally, some of the mutations listed here will be thought to be shared with other men in which case they might appear in upstream blocks on the tree. When this happens, the 'Blocks' field will indicate what block they appear in. Such a situation might arise with BigY men if the BED data suggests another man may be positive for a SNP, even though it doesn't appear in his VCF data. It might also happen if Chromo2 testing or Sanger sequencing of other men not on the tree show the SNP to be shared.

POS-REF-ALT (hg19) POS-REF-ALT (hg38) Blocks Names Region McDonald BED combBED STRBigY2
501829
22363102-T-A 20201216-T-A DYZ19 A+
13451224-C-T 11295548-C-T A*
20647400-C-G 18485514-C-G P4_Prx A*
20647405-C-G 18485519-C-G P4_Prx A*
22309762-T-G 20147876-T-G DYZ19 A*
22311093-C-A 20149207-C-A DYZ19 A*
22430869-T-G 20268983-T-G DYZ19 A*
22432200-C-A 20270314-C-A DYZ19 A*
24282956-C-T 22136809-C-T P3_t1 A*
22145411-TA-T 19983525-TA-T +
13820614-C-T 11699908-C-T BY51113 +
2886568-G-A 3018527-G-A BY57060 YY+
5851584-G-T 5983543-G-T BY58884 +
6985287-A-C 7117246-A-C BY62725 YY+
7204583-C-G 7336542-C-G YY+
7597919-G-A 7729878-G-A BY66161 YY+
7812998-T-G 7944957-T-G BY67878 YY+
8208967-A-G 8340926-A-G BY70762 YY8×T+
8291289-C-T 8423248-C-T BY71439 YY+
8695695-G-C 8827654-G-C BY75243 YY+
9832673-T-A 9995064-T-A YY+
13830531-C-T 11709825-C-T BY90862 +
15320279-A-G 13208385-A-G BY100813 YY+
16711672-T-C 14599792-T-C BY109550 YY+
16746334-G-A 14634454-G-A BY109756 YY+
17240026-T-C 15128146-T-C BY113224 YY+
18074016-G-C 15962136-G-C BY119710 YY+
18690961-C-T 16579081-C-T BY211787 YY+
19238714-G-C 17126834-G-C BY127579 YY+
19280516-A-G 17168636-A-G BY127920 YY+
19406637-A-G 17294757-A-G BY128835 YY+
20473499-TG-T 18311613-TG-T P5_Dst +
21801585-G-A 19639699-G-A BY135541 YY+
22436612-G-T 20274726-G-T BY218180 DYZ19 +
22460134-A-T 20298248-A-T FGC45888 DYZ19 +
22464250-G-A 20302364-G-A FGC52397 FT458342 DYZ19 +
22558416-A-G 20396530-A-G BY138999 YY+
22664859-T-C 20502973-T-C BY139886 YY+
23462216-G-C 21300330-G-C YY+
24424921-T-C 22278774-T-C BY149794 Y+
13160-C-A +
13179-A-G +
13186-A-G +
13452381-CCATTCCATTCCATTC-C,CCATTCCA 11296705-CCATTCCATTCCATTC-C,CCATTCCA *
22340326-G-T 20178440-G-T DYZ19 *
22300002-T-A 20138116-T-A DYZ19 *
9832619-A-G 9995010-A-G GG238Y18625 **
21409527-C-A 19247641-C-A Z42713 **
21834104-G-T 19672218-G-T Y2346 FGC7634 AM01342 **
58827401-T-C 56763470-A-G **
13212515-C-A 11056839-C-A **
5462791-G-T 5594750-G-T **
19036703-GTTT-G 16924823-GTTT-G 40×T**
20796384-C-A 18634498-C-A P4_Prx **
7107069-G-T 7239028-G-T **
9307559-G-T 9469950-G-T **
20991156-ACTG-A 18829270-ACTG-A P4_Dst **
17703287-G-C 15591407-G-C **
5796728-C-A 5928687-C-A **
6535445-C-A 6667404-C-A **
10653015-C-A **
10954317-A-T **
9940674-C-A 10103065-C-A **
10969084-A-T FT92137 **
26073111-C-A 23926964-C-A P1_Y1 **
10936198-GTTCCATTCCT-G **
10936224-C-T **
10936247-C-CACTCA **
10782877-C-A **
10667740-C-G **
10667742-G-C **
7211265-C-A 7343224-C-A **
15424272-C-CAA 13312392-C-CAA 11×A**
10850103-C-A **
3091981-C-A 3223940-C-A **
21353005-C-A 19191119-C-A **
8980524-C-A 9142915-C-A **
6037461-G-T 6169420-G-T **
23184811-C-A 21022925-C-A **
7253997-G-T 7385956-G-T **
18256138-A-G 16144258-A-G **
20116700-C-CA 18004820-C-CA P5_Dst **
24300814-T-TTC 22154667-T-TTC P3_t1 **
21556908-T-G 19395022-T-G **
56763516-A-T **
9193981-T-G 9356372-T-G **
14398395-C-A 12277691-C-A **
10778897-C-A **
17723008-C-A 15611128-C-A **
14300109-A-G 12179403-A-G **
14300110-T-A 12179404-T-A **
11658025-C-A **
24280873-G-T 22134726-G-T P3_t1 **
21551437-G-T 19389551-G-T **
10781579-A-T **
3130931-C-A 3262890-C-A **
14473589-C-A 12352858-C-A **
28781387-C-A 26635240-C-A **
25970738-C-CTA 23824591-C-CTA P1_Y1 **
10969090-C-A **
28773888-C-A 26627741-C-A **
10997718-C-CT **
10997720-AT-A **
10997747-T-TCCGAA **
17367770-C-A 15255890-C-A **
13259061-C-A 11103385-C-A **
24607323-T-TA 22461176-T-TA P3_t2 **
28730108-C-A 26583961-C-A **
3550713-C-A 3682672-C-A **
3252410-C-A 3384369-C-A **
10986309-C-A **
14574672-A-C 12462872-A-C **
10893678-C-A **
4087945-C-A 4219904-C-A **
21195808-G-T 19033922-G-T **
11019338-C-A **
18340632-G-T 16228752-G-T P6_Prx **
10896232-T-C **
11663060-T-A **
16783412-T-TAA 14671532-T-TAA 13×A**
10951373-C-A **
15116572-G-T 13004659-G-T **
13218726-T-C 11063050-T-C **
10971816-C-A **
5691278-T-C 5823237-T-C **
15234007-C-A 13122093-C-A **
15239008-C-A 13127094-C-A **
9436910-G-C 9599301-G-C FT149021 **
10968271-T-G **
20497568-T-TTC 18335682-T-TTC P5_Dst **
11028127-T-G **
10983635-T-C **
14779538-T-G 12667608-T-G **
6816754-C-G 6948713-C-G **
20125676-A-T 18013796-A-T P5_Dst **
6310850-C-G 6442809-C-G IR3_Dst **
5335917-C-A 5467876-C-A **
14395705-C-A 12275001-C-A **
18447603-C-A 16335723-C-A P6_Dst **
10755222-C-G **
10755246-C-A **
10942748-TTCCA-T **
4215848-G-T 4347807-G-T **
21316852-C-A 19154966-C-A **
15334670-C-A 13222788-C-A **
10873297-C-A **
10987566-C-A **
10921141-C-T **
2806230-TTA-T 2938189-TTA-T **
27780467-A-G 25634320-A-G P1_Y2 **
19775349-C-A 17663469-C-A P5_Prx **
3223443-T-C 3355402-T-C **
3232047-C-T 3364006-C-T **
3292032-G-T 3423991-G-T **
3360151-A-T 3492110-A-T **
3572943-G-T 3704902-G-T **
3627448-A-C 3759407-A-C **
3681310-G-T 3813269-G-T **
3829131-T-G 3961090-T-G **
4002034-A-T 4133993-A-T **
4013512-A-T 4145471-A-T **
4139578-C-A 4271537-C-A **
4265496-A-G 4397455-A-G FT341418 **
4315649-G-A 4447608-G-A **
4395427-C-A 4527386-C-A **
4447656-T-C 4579615-T-C **
4623836-T-C 4755795-T-C **
4778874-A-C 4910833-A-C **
4786543-G-T 4918502-G-T **
4945206-T-G 5077165-T-G **
4957080-T-G 5089039-T-G **
5000573-A-T 5132532-A-T **
5023737-T-G 5155696-T-G **
5212736-G-T 5344695-G-T **
5427434-G-T 5559393-G-T **
5455750-T-G 5587709-T-G **
5491528-T-A 5623487-T-A **
5515775-C-T 5647734-C-T **
5515783-G-A 5647742-G-A **
5515794-T-A 5647753-T-A **
5515799-T-C 5647758-T-C **
5515800-G-A 5647759-G-A **
5515807-CA-C 5647766-CA-C **
5614096-T-A 5746055-T-A **
5614105-C-A 5746064-C-A **
5619481-C-A 5751440-C-A **
5658646-G-T 5790605-G-T **
5658666-A-T 5790625-A-T **
5691295-C-CA 5823254-C-CA **
5796764-T-A 5928723-T-A **
5805884-C-A 5937843-C-A **
5929380-C-A 6061339-C-A **
6052665-A-T 6184624-A-T **
6114927-G-A 6246886-G-A **
6233728-A-AGT 6365687-A-AGT IR3_Dst **
6244224-A-G 6376183-A-G IR3_Dst **
6353823-T-C 6485782-T-C **
6505864-T-A 6637823-T-A **
6642023-C-A 6773982-C-A **
6776190-G-A 6908149-G-A **
6826793-C-A 6958752-C-A **
7042872-T-C 7174831-T-C FTB35280 **
7048097-A-T 7180056-A-T **
7078407-T-A 7210366-T-A **
7093486-G-T 7225445-G-T **
7156065-G-T 7288024-G-T **
7159209-G-T 7291168-G-T **
7225467-C-G 7357426-C-G **
7269387-A-C 7401346-A-C **
7313336-C-A 7445295-C-A **
7866061-C-A 7998020-C-A **
8856893-T-G 8988852-T-G **
9109856-C-A **
9193997-T-G 9356388-T-G **
9520153-T-C 9682544-T-C **
9927528-A-C 10089919-A-C **
9949208-G-T 10111599-G-T **
10653035-C-A **
10655911-T-G **
10660385-C-A **
10660447-C-A **
10678679-A-AC **
10683180-C-A **
10748389-A-T **
10753856-T-G **
10773437-C-A **
10790187-T-A **
10800631-A-C **
10800961-A-T **
10811075-C-A **
10816057-TTCCA-T **
10849115-C-A **
10851284-A-T **
10860757-T-C **
10864493-C-A FT377108 **
10893685-T-A **
10895482-T-A **
10931459-C-A **
10944099-AAA-C **
10944104-C-G **
10946845-A-G **
10946909-CCCAAT-C **
10949760-T-A **
10976981-T-A **
10979015-C-A **
10990783-C-A **
10999204-C-T FT439824 **
11018526-T-C **
11027391-C-A **
11037158-C-A **
13233219-T-G 11077543-T-G **
13393206-C-A 11237530-C-A **
13429763-G-T 11274087-G-T **
11674712-T-A **
13935694-C-A 11814988-C-A **
13936289-A-C 11815583-A-C **
13936291-A-C 11815585-A-C **
13936319-G-T 11815613-G-T **
13947797-G-T 11827091-G-T **
13984496-A-C 11863790-A-C **
14009398-G-T 11888692-G-T **
14013887-G-T 11893181-G-T **
14030277-C-A 11909571-C-A **
14075465-C-A 11954759-C-A **
14241227-A-G 12120521-A-G **
14273089-T-A 12152383-T-A **
14380977-A-C 12260273-A-C **
14422707-T-A 12301982-T-A **
14508704-C-A 12396909-C-A **
14533103-CT-C 12421304-CT-C **
14742341-A-C 12630409-A-C **
14779546-C-G 12667616-C-G **
14779548-C-G 12667618-C-G **
14779576-T-A 12667646-T-A **
14794637-C-T 12682708-C-T **
14926391-A-C 12814456-A-C **
15186976-T-C 13075062-T-C **
15279377-G-C 13167476-G-C FT149263 **
15286568-G-T 13174667-G-T **
15370164-G-A 13258284-G-A **
15475057-C-A 13363177-C-A **
15599990-T-G 13488110-T-G **
15631499-G-T 13519619-G-T **
15741486-T-C 13629606-T-C **
15882715-C-A 13770835-C-A **
16290879-C-A 14178999-C-A **
16607877-T-G 14495997-T-G **
16621177-G-C 14509297-G-C FT22871 **
16621843-C-A 14509963-C-A **
16708351-T-A 14596471-T-A **
16941630-A-T 14829750-A-T **
17071314-G-A 14959434-G-A **
17083117-G-A 14971237-G-A **
17125248-T-A 15013368-T-A **
17212212-G-C 15100332-G-C **
17219824-A-G 15107944-A-G **
17486204-T-A 15374324-T-A **
17545467-C-G 15433587-C-G **
17722924-G-A 15611044-G-A **
18050524-A-C 15938644-A-C **
18053639-C-A 15941759-C-A **
18143870-A-G 16031990-A-G **
18324412-G-T 16212532-G-T P6_Prx **
18324414-C-A 16212534-C-A P6_Prx **
18324427-T-A 16212547-T-A P6_Prx **
18324441-T-A 16212561-T-A P6_Prx **
18324458-C-A 16212578-C-A P6_Prx **
18328660-T-A 16216780-T-A P6_Prx **
18480201-T-A 16368321-T-A P6_Dst **
18789862-G-T 16677982-G-T **
18794132-A-C 16682252-A-C **
18859269-T-A 16747389-T-A **
19121886-A-C 17010006-A-C **
19129545-G-C 17017665-G-C **
19270559-T-AA 17158679-T-AA **
19301504-C-A 17189624-C-A **
19737269-T-A 17625389-T-A P5_Prx **
19737282-C-A 17625402-C-A P5_Prx **
19891019-A-T 17779139-A-T P5_Prx **
20125671-A-T 18013791-A-T P5_Dst **
20125675-A-T 18013795-A-T P5_Dst **
20473507-G-A 18311621-G-A P5_Dst **
20473509-G-C 18311623-G-C P5_Dst **
20570220-C-G 18408334-C-G P5_Dst **
20579143-T-TAC 18417257-T-TAC P5_Dst **
20622946-A-T 18461060-A-T P4_Prx **
20729525-C-A 18567639-C-A P4_Prx **
20733021-A-T 18571135-A-T P4_Prx **
21037490-G-T 18875604-G-T **
21371103-T-G 19209217-T-G **
21513821-C-A 19351935-C-A **
21584910-C-A 19423024-C-A **
21834110-G-T 19672224-G-T **
21834115-T-A 19672229-T-A **
21834130-G-T 19672244-G-T **
21834132-T-A 19672246-T-A **
22044138-C-G 19882252-C-G **
22204306-T-C 20042420-T-C **
22787243-T-G 20625357-T-G **
22979981-G-C 20818095-G-C **
23127592-G-T 20965706-G-T **
23277350-T-G 21115464-T-G **
23373005-C-A 21211119-C-A **
23381035-A-T 21219149-A-T **
21753864-A-T **
24280866-A-T 22134719-A-T P3_t1 **
24280870-C-A 22134723-C-A FT460915 P3_t1 **
24280878-T-A 22134731-T-A P3_t1 **
24884249-C-A 22738102-C-A g1 **
25580558-T-G 23434411-T-G P1_gr1 **
26046102-G-T 23899955-G-T P1_Y1 **
26073075-TG-T 23926928-TG-T P1_Y1 **
26073117-A-T 23926970-A-T P1_Y1 **
26328645-G-T 24182498-G-T P1_Y1 **
28441439-T-A 26295292-T-A P1_gr2 **
28460861-A-G 26314714-A-G FT150196 **
28561807-G-T 26415660-G-T **
28582696-C-A 26436549-C-A **
28715587-A-G 26569440-A-G **
28738416-G-T 26592269-G-T **
56842197-T-A **
12986-T-C **
12991-G-T **
12995-A-G **
12998-C-T **
9930097-G-A 10092488-G-A ***
9930110-G-T 10092501-G-T ***
10926683-C-T ***
4064099-C-A 4196058-C-A ***
10887194-G-T ***
7723810-AAGAG-A 7855769-AAGAG-A 9×AG***
56843603-G-T ***
7784591-C-CT 7916550-C-CT 9×T***
10683197-C-A ***
15975280-C-A 13863400-C-A ***
9116727-G-T 9279118-G-T ***
10766464-C-A ***
56861670-C-A ***
15581093-CTTT-C,CT 13469213-CTTT-C,CT 16×T***
21086158-AAAC-A 18924272-AAAC-A ***
10992667-C-A ***
13579749-G-T 11424073-G-T ***
11019732-T-A ***
9041001-C-A 9203392-C-A ***
10651608-C-A,G ***
10654595-A-G ***
10663023-T-TCCATA ***
10691189-T-C ***
10779315-C-A ***
13643611-T-A 11487935-T-A ***
14557751-G-T 12445952-G-T ***
15124097-A-G 13012184-A-G ***
17371023-C-T 15259143-C-T ***
19303640-C-A 17191760-C-A ***
21836738-CTTT-C,CTTTT 19674852-CTTT-C,CTTTT 15×T***
23475631-G-T 21313745-G-T ***
24433386-G-T 22287239-G-T ***
24573231-T-C 22427084-T-C P3_t2 ***
56843609-A-G ***

In the table above, the meaning of the confidence field depends on whether the data comes from an FTDNA kit or an FGC kit. For FTDNA kits, + implies a "PASS" result with just one possible variant, * indicates a "PASS" but with multiple variants, ** indicates "REJECTED" with just a single variant, and *** indicates "REJECTED" with multiple possible variants. 'A*' are heterozygous variants not called by FTDNA, but still pulled from the VCF file. For FGC kits, + indicates over 99% likely genuine (95% for INDELs); * over 95% likely genuine (90% for INDELs); ** about 40% likely genuine; *** about 10% likely genuine. Manual entries read directly from a BAM file will be either + indicating positive, or * indicating that the data show a mixture of possible variants.

For the FTDNA kits, the BED data is encoded in the background color of the cells. Those cells with a white background have coverage, those with a grey background indicate no coverage in the BED file, and those with a pink background indicate the mutation is on the edge of a coverage region. These pink regions often indicate that the individual may be positive for a SNP even if there is no corresponding entry in the vcf file.

The combBED column indicates whether or not the mutation is a SNP and falls in the combBED region defined in Defining a New Rate Constant for Y-Chromosome SNPs based on Full Sequencing Data by Dmitry Adamov, Vladimir Guryanov, Sergey Karzhavin, Vladimir Tagankin, Vadim Urasin.

The McDonald BED column indicates whether or not the mutation is a SNP and falls in the BED region used by Dr. Iain McDonald in the age analysis he does for R-U106 men.